• A case report of mesalazine-induced lung injury: A reversible drug side effect 

      Kotsiou O.S., Gourgoulianis K.I. (2019)
      Introduction: Mesalazine is widely used in the treatment of the acute and maintenance phase of ulcerative colitis (UC). The possibility of interstitial lung disease being induced by mesalazine in the form of eosinophilic ...
    • CD8+T lymphocytes in bronchoalveolar lavage in idiopathic pulmonary fibrosis 

      Papiris, S. A.; Kollintza, A.; Karatza, M.; Manali, E. D.; Sotiropoulou, C.; Milic-Emili, J.; Roussos, C.; Daniil, Z. (2007)
      Background. Recently it was shown that in Idiopathic Pulmonary Fibrosis (IPF) tissue infiltrating CD8+ T lymphocytes (TLs) are associated with breathlessness and physiological indices of disease severity, as well as that ...
    • Combined pulmonary fibrosis and emphysema characteristics in a Greek cohort 

      Malli F., Papakosta D., Antoniou K., Dimadi M., Polychronopoulos V., Malagari K., Oikonomou A., Bouros D.E., Daniil Z. (2019)
      Background: Combined pulmonary fibrosis and emphysema (CPFE) has recently received great attention, with studies suggesting that it presents a distinct clinical entity while others have challenged this hypothesis. This ...
    • Concurrent cardiac sarcoidosis and obstructive sleep apnea presenting as arrhythmias 

      Malli F., Bardaka F., Gourgoulianis K.I., Daniil Z. (2020)
      Background: Cardiac involvement is a rare and potentially fatal presentation of sarcoidosis. Obstructive sleep apnea may complicate sarcoidosis. Case presentation: We report a case of a sarcoidosis patient with cardiac ...
    • Early bacterial identification among intubated patients with COVID-19 or influenza pneumonia: A european multicenter comparative clinical trial 

      Rouzé A., Martin-Loeches I., Povoa P., Metzelard M., Cheyron D.D., Lambiotte F., Tamion F., Labruyere M., Geronimi C.B., Nieszkowska A., Nyunga M., Pouly O., Thille A.W., Megarbane B., Saade A., Diaz E., Magira E., Llitjos J.-F., Cilloniz C., Ioannidou I., Pierre A., Reignier J., Garot D., Kreitmann L., Baudel J.-L., Fartoukh M., Plantefeve G., Beurton A., Asfar P., Boyer A., Mekontso-Dessap A., Makris D., Vinsonneau C., Floch P.-E., Weiss N., Ceccato A., Artigas A., Bouchereau M., Duhamel A., Labreuche J., Nseir S., Poissy J., Favory R., Preau S., Jourdain M., Boyd S., Coelho L., Maizel J., Cuchet P., Zarrougui W., Boyer D., Quenot J.-P., Imouloudene M., Luyt C.-E., van der Linden T., Bardin J., Voicu S., Azoulay E., Goma G., Pene F., Torres A., Thevenin D., Ehrmann S., Argaud L., Guidet B., Voiriot G., Contou D., Le Marec J., Demiselle J., Meguerditchian D., Razazi K., Tsolaki V., Sejourne C., Brunin G., LeGuennec L., Morales L., the coVAPid Study Group (2021)
      Rationale: Early empirical antimicrobial treatment is frequently prescribed to critically ill patients with coronavirus disease (COVID-19) based on Surviving Sepsis Campaign guidelines. Objectives: We aimed to determine ...
    • Incorporating Biomarkers in COPD Management: The Research Keeps Going 

      Pantazopoulos I., Magounaki K., Kotsiou O., Rouka E., Perlikos F., Kakavas S., Gourgoulianis K. (2022)
      Globally, chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality, having a significant socioeconomic effect. Several molecular mechanisms have been related to COPD including chronic ...
    • Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study 

      Rouzé A., Martin-Loeches I., Povoa P., Makris D., Artigas A., Bouchereau M., Lambiotte F., Metzelard M., Cuchet P., Boulle Geronimi C., Labruyere M., Tamion F., Nyunga M., Luyt C.-E., Labreuche J., Pouly O., Bardin J., Saade A., Asfar P., Baudel J.-L., Beurton A., Garot D., Ioannidou I., Kreitmann L., Llitjos J.-F., Magira E., Mégarbane B., Meguerditchian D., Moglia E., Mekontso-Dessap A., Reignier J., Turpin M., Pierre A., Plantefeve G., Vinsonneau C., Floch P.-E., Weiss N., Ceccato A., Torres A., Duhamel A., Nseir S., Favory R., Preau S., Jourdain M., Poissy J., Bouras C., Saint Leger P., Fodil H., Aptel F., Van Der Linden T., Thille A.W., Azoulay E., Pène F., Razazi K., Bagate F., Contou D., Voiriot G., Thevenin D., Guidet B., Le Guennec L., Kouatchet A., Ehrmann S., Brunin G., Morawiec E., Boyer A., Argaud L., Voicu S., Nieszkowska A., Kowalski B., Goma G., Diaz E., Morales L., Tsolaki V., Gtavriilidis G., Mentzelopoulos S.D., Nora D., Boyd S., Coelho L., Maizel J., Du Cheyron D., Imouloudene M., Quenot J.-P., Guilbert A., Cilloniz C., on behalf of the coVAPid study Group (2021)
      Purpose: Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired infections is low. We aimed ...
    • A specific phospholipase C activity regulates phosphatidylinositol levels in lung surfactant of patients with acute respiratory distress syndrome 

      Spyridakis, S.; Leondaritis, G.; Nakos, G.; Lekka, M. E.; Galanopoulou, D. (2010)
      Lung surfactant (LS) is a lipid-rich material lining the inside of the lungs. It reduces surface tension at the liquid/air interface and thus, it confers protection of the alveoli from collapsing. The surfaceactive component ...
    • Th1/Th2 cytokine pattern in bronchoalveolar lavage fluid and induced sputum in pulmonary sarcoidosis 

      Tsiligianni, I.; Antoniou, K. M.; Kyriakou, D.; Tzanakis, N.; Chrysofakis, G.; Siafakas, N. M.; Bouros, D. (2005)
      Background: Sarcoidosis is thought to be a T-helper type 1 cytokine (Th2 cytokine) mediated disorder. Induced sputum (IS) has been proposed as a useful non-invasive method, mainly for the assessment of the airway diseases. ...